What a heck. Installed a fresh Suse tumbleweed and Twitch is not running. All Browsers have an error 4000.

You must install some codecs. How it works?

openSUSE Tumbleweed:

sudo zypper addrepo -cfp 90 'https://ftp.gwdg.de/pub/linux/misc/packman/suse/openSUSE_Tumbleweed/' packman

openSUSE Leap:

sudo zypper addrepo -cfp 90 'https://ftp.gwdg.de/pub/linux/misc/packman/suse/openSUSE_Leap_$releasever/' packman

for all systems the same command

sudo zypper refresh
sudo zypper dist-upgrade --from packman --allow-vendor-change

sudo zypper install --from packman ffmpeg gstreamer-plugins-{good,bad,ugly,libav} libavcodec-full vlc-codecs

thats it

found here

How To Install Multimedia Codecs In OpenSUSE